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The pathophysiology of anemia and the basis of its clinical investigation. Pruebas que evalúan el estado del hierro: Hierro del compartimiento funcional: Ferremia: Capacidad total de saturación de hierro (CTSH). Transcript of Clasificacion de anemias. Disminución de la capacidad transportadora de oxigeno de la sangre. Adaptaciones fisiológicas.

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Classification of anemias Anemias can be classified by cytometric schemes anemiaz. The measurement of erythrocyte folate is a difficult technique that is not available in every laboratory. Redistribution of blood flow In anemia selective vasoconstriction of blood vessels subserving certain nonvital areas allows more blood to flow into critical areas.

Classification of anemia for gastroenterologists

In the absence of intake of any of the drugs mentioned above or alcohol, the most frequent cause of microcytic anemia is nutritional deficiency[ 50 ]. Abstract Most anemia is related to the digestive system by dietary deficiency, malabsorption, or chronic bleeding. Pancytopenia may be caused by intrinsic [bone marrow aplasia, leukemia, myelodysplastic syndrome MDS anemiaz myelofibrosis] or extrinsic metastasis, Gaucher disease and other thesaurismosis, tuberculosis, histoplasmosis, viral and parasitic infections.

Journal List World J Gastroenterol v. The normoregenerative anemias are in contrast to those characterized by inadequate marrow response to the degree of anemia.

Laboratory measurement of haptoglobin is fairly easy and yields useful information to assist in documenting decreased rbc life span. The most frequent cause of chronic anemia is gastrointestinal pathology, classificacion this explains why patients with anemia are often sent for consultation to a clasificaclon specialist[ 8 ].

Therefore, when the bone marrow shows a normal regenerative capacity, there should be an inverse relationship between the decrease in hemoglobin and the increased number of reticulocytes regenerative anemia. Digestive diseases potentially causing anemia have been clasifiicacion in preference, but other causes of anemia have been included in the text and tables.

The bilirubin is greedily scarfed up by the liver, conjugated with glucuronide, squirted into the clasififacion tract in the bile, and converted to urobilinogen by evangelical colonic bacteria.


Prevalence and causes of anemia in elderly hospitalized patients. Am J Clin Nutr. In men and postmenopausal women, the bigger concern should be to rule out the presence of occult bleeding. Gastroenterol Clin North Am. Racial variation in the relationship of anemia with mortality and mobility disability among older adults. Author information Xe notes Copyright and License information Disclaimer.

Should it not find the succor of oxygen, it would escape to a feral existence of unsavory chemical reactions, where it would find itself in the company of the opprobrious Free Radicals, miscreants whose only purpose is the steric vandalism of the macromolecular cathedrals of life. Anemia caused by nutritional deficiencies or decreased production of erythropoietin is much more frequent than that caused by a primitive defect in bone marrow.

It should always be borne in mind that MCV is an average value and therefore does not provide information about the homogeneity of the erythrocyte population.

Other parameters of iron metabolism serum iron, total transport capacity of iron, and transferrin are unable to distinguish with certainty IDA from ACD[ 23 ]. Synchronous upper and lower gastrointestinal endoscopy is an effective method of investigating iron-deficiency anaemia. Serum unconjugated bilirubin and urine urobilinogen concentration When red cells, at the end of their day life-span, go to the great spleen in the sky, they are systematically dismantled.

Existen tres tipos de trascobalaminas: When progenitor red cells are impaired selectively, bone marrow erythroblasts are much reduced or absent, while other hematological cellular lines remain normal.

Clasificación morfológica de las anemias by Ernesto Griego Melo on Prezi

The reticulocyte count is useful to distinguish anemia in which there is an appropriate bone marrow response from that in which there is a decrease in the production of erythrocytes.

In contrast to pure red cell aplasia, the bone marrow is rich in erythroblasts in patients with dyserythropoiesis. Clxsificacion are important to guide ed diagnosis. Cobalamin deficiency Poor diet Deficiency of intrinsic factor Pernicious anemia Total or partial Gastrectomy Ingestion of caustic lye Functional defect of intrinsic factor Alteration of ileal microenvironment Insufficient pancreatic protease activity Inactivation enzyme Sd.


Clinical manifestations and classification of erytrocyte disorders. These are the hyporegenerative anemias. This article has ds cited by other articles in PMC. Pathogenic mechanisms involved in the production of anemia are very simple: It is rare, but it should be noted that gastric or intestinal lymphoma sometimes presents as mild anemia with nonspecific gastrointestinal symptoms. Los reflejos pueden estar atenuados o exaltados.

Anemia: Pathophysiology, Classification, Clinical Investigation

These parameters allow the diagnosis of borderline patients who, at another time, would have undergone unnecessary investigation of iron in the bone marrow[ 30 – 32 ]. Last, but not abemias, the liver plays an essential role in the control of iron metabolism through the hepcidin pathway, and accounts for most vitamin B12, folate and iron stores. Diagnosis of megaloblastic anemia. The exploration that leads directly to diagnosis is gastroscopy, with mucosal biopsy and study of antiparietal cell antibodies.

Beutler has proposed a lower limit of hemoglobin g less in African Americans than in Caucasians.

ACD is the most frequent cause of anemia after ferropenia[ 4142 ]. The distribution of nutrient-deficiency anemia in the elderly is: The simple analysis of different parameters provided by the hematological analyzer ane,ias a diagnosis of microcytic anemia.

ACD is the most prevalent form of anemia after IDA in the general population[ 4068 ], but is even more common in hospitalized patients, regardless of sex and age[ 42676970 ].

The concentration of reticulocytes reports on the bone marrow response to anemia.